Malignant cells are always broken” genetically – their properties are directly relat to mutations in DNA that affect their reproduction, growth and mechanisms of recovery – repair – of the cell genome. The main genes that, and tumor growth suppressors. For example, mutat proto-oncogenes can trigger the process of abnormal, very rapid and uncontroll division of damag cells and malignant growth. And the mutation and loss of function of tumor suppressor genes, which help detect DNA damage and start the process of destroying the “wrong” cell, can lead to the development of a malignant tumor.
When mutat cause cancer are proto
In addition to DNA damage the development of the Spain Phone Numbers List disease is influenc by external factors: viruses (for example, hepatitis B and C viruses, some strains of human papillomavirus, HIV, some types of herpes viruses), bacteria, for example, Helicobacter pylori, parasites, radiation, drugs (mainly , hormonal), nutrition, lifestyle and much more. inflammation and organ damage, due to which cell division is accelerat. A “broken” cell does not work according to the rules of the body: it begins to divide abnormally quickly and uncontrollably, not responding to signals and not self-destructing, as it happens normally with cellular breakdowns.
Different types of drugs are us
A malignant tumor arises and grows, which disrupts BT Lists the function of the organ and metastasizes with lymph, blood and other routes to different organs. Metastases, in turn, can move to other organs. Most often, a person dies from metastases, and not from the primary tumo How Cancer Immunotherapy Works it recognizes and destroys them, but this process can be disturb: some cells avoid detection and continue to multiply. to force the immune system to find and destroy cancer cells. For example, checkpoint inhibitors deactivate protective proteins on the surface of malignant cells, helping the immune system to recognize them. Some immunomodulators can activate.